Semax is a synthetic peptide similar to adrenocorticotropic hormone (ACTH), originally developed for the treatment of cognitive disorders and brain injuries. In research fields, it is widely recognized for its potent nootropic and neuroprotective properties. Its mechanism of action works by modulating the brain's cholinergic and dopaminergic systems.

This peptide promotes the expression of neurotrophic factors such as brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF), which are critical for neuronal survival and growth. Semax has been studied to improve cognitive function, mitigate the effects of oxidative stress, and facilitate functional recovery following ischemic or traumatic injuries.